Publications

Kelso T.W.R., Porter D.K., Amaral M.L., Shokhirev M.N., Benner C., Hargreaves D.C. Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers. Elife. 2017 Oct 2;6. pii: e30506. doi: 10.7554/eLife.30506. [read more]

Miller E.L., Hargreaves D.C., Kadoch C., Chang C.Y., Calarco J.P., Hodges C., Buenrostro J.D., Cui K., Greenleaf W.J., Zhao K., Crabtree G.R. (2017) TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nat Struct Mol Biol. 24(4):344-352.

Kadoch, C.*, Hargreaves, D.C.*, Hodges, C., Elias, L., Ho, L., Ranish, J., Crabtree, G.R. (2013) Proteomic and Bioinformatic Analysis of mSWI/SNF (BAF) Complexes Reveals Extensive Roles in Human Malignancy. Nature Genetics. 45(6), 592-601.

Dykhuizen, E.C.*, Hargreaves, D.C.*, Miller, E., Cui, K., Korshunov, A., Kool, M., Pfister, S., Cho, Y-J., Zhao, K., Crabtree, G.R Crabtree, G.R. (2013) BAF (mSWI/SNF) Complexes Cooperate with Topoisomerase II? to Decatenate DNA. Nature. 497(7451), 624-627.

Hargreaves, D.C. and G.R. Crabtree. (2011) ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Research 21(3), 396-420.

Hargreaves, D.C., Horng, T., Medzhitov, R. (2009) Control of inducible gene expression by signal-dependent transcriptional elongation. Cell. 138(1), 129-145.

Foster, S.L.*, Hargreaves, D.C.*, Medzhitov, R. (2007) Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature. 447(7147), 972-8.

Hargreaves, D.C. and R. Medzhitov. (2005) Innate Sensors of Microbial Infection. J. Clin. Immunol. 25(6), 503-10.

Cyster, J.G., Ansel, K.M., Ngo, V.N., Hargreaves, D.C., Lu, T.T. (2002) Traffic patterns of B cells and plasma cells. Adv Exp Med Biol. 512, 35-41.

Luther, S., Bidgol, A.*, Hargreaves, D.C.*, Schmidt, A., Xu, Y., Paniyadi, J., Matloubian, M., Cyster, J.G. (2002) Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J. Immunol. 169(1), 424-33.

Hargreaves, D.C.*, Hyman P.L.*, Lu, T.T., Ngo, V.N., Bidgol, A., Suzuki, G., Zou, Y., Littman, D.R., Cyster, J.G. (2001) A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 194(1), 45-56.

*these authors contributed equally to this work.