Hargreaves Lab
Principal Investigator

Diana Hargreaves

Principal Investigator

Diana received her Bachelor of Science from Haverford College and subsequently worked with Dr. Jason Cyster at the University of California, San Francisco. She completed her doctoral training in the Yale Immunobiology Department with Dr. Ruslan Medzhitov under an NSF Graduate Fellowship where she studied epigenetic and transcriptional mechanisms regulating immune response genes. She went on to focus on the SWI/SNF complex in her postdoctoral studies at Stanford University under Dr. Gerald Crabtree. During that time, she was the recipient of the Helen Hay Whitney Foundation Postdoctoral Fellowship, the Ann Schreiber Research Training Program of Excellence Award, and the K99/R00 Pathway to Independence Award. She enjoys spending time outdoors with her sons.
Research Associates

Jovylyn Gatchalian

Research Associate

Jovylyn Gatchalian received her B.S. in Biochemistry/Chemistry from the University of California, San Diego and upon graduating, conducted research at The Scripps Research Institute in Dr. John Elder and Dr. Raymond Stevens’ labs. She then pursued her PhD in Pharmacology at the University of Colorado Anschutz Medical Campus under the mentorship of Dr. Tatiana Kutateladze. She was an NCI NRSA pre-doctoral fellow and her studies focused on the structural characterization of histone PTM recognition by epigenetic reader domains. She is now a Research Associate in the Hargreaves lab, where she is defining the composition of the mammalian BAF complex in the normal and oncogenic states and investigating how their differences affect the localization and remodeling activity of the complex. Outside of the lab, she enjoys hiking and camping and though it’s rare these days, she also likes to go indoor climbing.

Fangjian Gao

Research Associate

Fangjian received his Bachelor of Biological Science from Fudan University, Shanghai, China. Later, he completed his PhD training in University of Texas Health Science Center at San Antonio with Dr. Thomas Boyer where he worked on understanding transcription regulation through Mediator complex during development. He joined Hargreaves as a postdoctoral research associate and is currently focused on the SWI/SNF complex and its role in epigenetic transcription regulation. In 2017, he received the Salk Pioneer Fund Postdoctoral Scholar Award.
Helen McRae

Helen McRae

Research Associate

Helen received her B.Sc (Hons) majoring in genetics from the University of Melbourne in Australia. She completed her PhD through the Walter and Eliza Hall Institute of Medical Research in Melbourne Australia in the laboratory of Anne Voss and Tim Thomas where she studied the in vivo role of PHF6 in haematopoietic development and leukaemia. Helen joined the Hargreaves lab in September 2019 and is investigating the role of BAF complex subunits in the tumour microenvironment. Outside of the lab, some of Helen’s favourite activities include running, karaoke and swimming in the ocean.
Research Assistants

Nick Elliott

Research Assistant


Josephine Ho

Research Assistant

Josephine received her bachelor’s and master’s degrees from Wesleyan University, where she studied molecular biology and biochemistry. She is currently running genomic assays to study the role of BAF complexes in immune response. When not in lab, she enjoys spacing out on the beach.
Graduate Students

Jingwen Liao

Graduate Student

Jingwen was born and raised in Shanghai, China before she moved to the US for high school. She graduated from Scripps College in Claremont, CA in 2018 and enrolled in UCSD Biological Sciences PhD program right afterwards. She joined Diana Hargreaves lab in 2019 to study the role of BAF complex in macrophage development and activation. Outside the lab, Jingwen enjoys snowboarding, making/searching for good food, and goofing around with her dog.

Matthew Maxwell

Graduate Student

Matt grew up in a small town in rural Oklahoma and graduated Summa Cum Laude from Southeastern Oklahoma State University with a B.S in Biochemistry. During his undergraduate years, he studied hypoxia signaling in cancer in the lab of Dr. Teresa Golden and completed summer research fellowships at Harvard, UCLA, and Novartis. Matt matriculated into the UCSD Biological Sciences PhD program in 2018 and joined the Hargreaves lab in early 2019. Outside of the lab, Matt enjoys spending time in the ocean, reading, and grabbing a beer with his friends and lab mates.
Administrative Assistant

Shawn Boggs

Administrative Assistant

Hargreaves Lab Alumni

Shivani Malik

Senior Research Scientist
Kura Oncology, Inc.

Devin Porter

Scientist I
UST Corporation

Timothy Kelso

Research Services and Projects Officer
Hunter Medical Research Institute, Australia

Jawoon Yi

Graduate Student
Chonnam National University, Korea