Salk Institute

Hargreaves Lab
Hargreaves Lab


Principal Investigator

Diana Hargreavesdhargreaves@salk.eduDiana received her Bachelor of Science from Haverford College and subsequently worked with Dr. Jason Cyster at the University of California, San Francisco. She completed her doctoral training in the Yale Immunobiology Department with Dr. Ruslan Medzhitov under an NSF Graduate Fellowship where she studied epigenetic and transcriptional mechanisms regulating immune response genes. She went on to focus on the SWI/SNF complex in her postdoctoral studies at Stanford University under Dr. Gerald Crabtree. During that time, she was the recipient of the Helen Hay Whitney Foundation Postdoctoral Fellowship, the Ann Schreiber Research Training Program of Excellence Award, and the K99/R00 Pathway to Independence Award. She enjoys spending time outdoors with her sons.

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Research Associates

Fangjian Gaofgao@salk.eduFangjian received his Bachelor of Biological Science from Fudan University, Shanghai, China. Later, he completed his PhD training in University of Texas Health Science Center at San Antonio with Dr. Thomas Boyer where he worked on understanding transcription regulation through Mediator complex during development. He joined Hargreaves as a postdoctoral research associate and is currently focused on the SWI/SNF complex and its role in epigenetic transcription regulation. In 2017, he received the Salk Pioneer Fund Postdoctoral Scholar Award.

Jovylyn Gatchalianjgatchalian@salk.eduJovylyn Gatchalian received her B.S. in Biochemistry/Chemistry from the University of California, San Diego and upon graduating, conducted research at The Scripps Research Institute in Dr. John Elder and Dr. Raymond Stevens’ labs. She then pursued her PhD in Pharmacology at the University of Colorado Anschutz Medical Campus under the mentorship of Dr. Tatiana Kutateladze. She was an NCI NRSA pre-doctoral fellow and her studies focused on the structural characterization of histone PTM recognition by epigenetic reader domains. She is now a Research Associate in the Hargreaves lab, where she is defining the composition of the mammalian BAF complex in the normal and oncogenic states and investigating how their differences affect the localization and remodeling activity of the complex. Outside of the lab, she enjoys hiking and camping and though it’s rare these days, she also likes to go indoor climbing.

Timothy Kelsotkelso@salk.eduTim is interested in understanding how mutations in chromatin remodeling complexes drive cancer, with the aim of uncovering novel vulnerabilities for therapeutic targeting. He joined the Hargreaves lab as a postdoctoral research associate in November, 2015, having received his Ph.D. as part of the International Max Planck Research School in Germany from the University of Muenster. Before moving to Europe, Tim completed his undergraduate training at the University of Newcastle in his hometown in Australia. In 2016, he was awarded the Genentech Foundation Fellowship Award for study in the area of signal transduction and cancer. Outside the lab, Tim enjoys surfing, touch rugby, and travelling.

Research Collaborator

Shivani Maliksmalik@salk.eduShivani received her Bachelor of Science and Master of Science degrees from University of Calcutta, India. She came to the US to pursue her doctoral degree at the Southern Illinois University at Carbondale, Illinois. Her Ph.D. work focused on regulatory mechanisms of transcription and associated DNA damage repair in yeast. She received excellence award for outstanding graduate research student and outstanding dissertation award for her doctoral work. She went on to work in labs of Dr. Katrin Chua (at Stanford) and Dr. Eric Collisson (at University of California, San Francisco) to study the roles of epigenetic modifiers in cancer progression. She enjoys hiking with her dog.

Administrative Assistant

Megan Mornmmorn@salk.eduMegan received her B.S. in Biology at the University of Illinois Champaign-Urbana with an emphasis in Marine Biology and course work completed at the University of Hawaii at Hilo. After graduating, she worked in a flow cytometry lab and in an aquarium with marine mammals. She then lived in China for several years completing her M.A. in Anthropology and Asian Religion from the University of London School of Asian and African Studies. Her work mainly focused on elements of Chinese and Japanese Esoteric Buddhism and its Relationship to Asian Shamanism. She enjoys surfing, playing with her dogs and drinking craft beers.

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